Research output per year
Research output per year
Personal profile
About
Dr. Johnson joined the Department of Natural Sciences and Mathematics in 2014. He received a B.A. in Molecular Cellular and Development Biology and a PhD in Chemical Oceanography from UC Santa Cruz. He conducted postdoctoral studies at UC Berkeley in collaboration with UC Davis, UC Santa Cruz and UCSF. His background is in the area of analytical, bioorganic and medicinal chemistry with an emphasis in biomedical research involving natural products. The goal of the Johnson laboratory is to chemically validate biologically active terrestrial and marine-derived natural products to serve as: a) therapeutic lead molecular structures to treat cancer, inflammation, neurobiological and aging disorders or b) novel probes in chemical biology research.
Contact Information
Dominican University of California
50 Acacia Ave.
San Rafael, CA 94901
Related documents
Education/Academic qualification
Chemical Oceanography - Marine Natural Products Chemistry, PhD, University of California, Santa Cruz
2008
Molecular, Cellular and Developmental Biology, BA, University of California, Santa Cruz
1999
Research Interests
- terrestrial and marine-derived natural products to serve as therapeutic lead molecular structures that affect specific targets in biomedical research involving oncology and neuroscience
Disciplines
- Biomedical
- Biochemistry
- Natural Products Chemistry and Pharmacognosy
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In Vivo Evaluation & Thermolysis of Zampanolide Reveals Delayed Binding Mode of Dactylolide and Cytotoxicity of N-acyl-hemiaminal Side Chain
Johnson, T., 2025.Research output: Contribution to conference › Poster › peer-review
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Further Probing the Properties of a Unique Sponge-derived Alkaloid Through the Isolation of a New (-)-(5E)-(8R)-(14Z)-Mycothiazole Analogue
Gerke, J. A., Odron, S. F., Kim, J., Dutta, N., Clarke, J. G., Media, J., Coppage, D. A., Oorloff, M., Alcala, A., Garcia, G., Kang, M. E. F., Gerke, C. L., Peterson, J. C., Morris, J. D., Higuchi-Sanabria, R., Valeriote, F. A., Crews, P. & Johnson, T., Sep 30 2024, In: Journal of Natural Products. 87, 10, p. 2523–2529Research output: Contribution to journal › Article › peer-review
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Investigating Impacts of the Mycothiazole Chemotype as a Chemical Probe for the Study of Mitochondrial Function and Aging
Dutta, N., Gerke, J. A., Odron, S. F., Morris, J. D., Hruby, A., Kim, J., Castro Torres, T., Shemtov, S. J., Clarke, J. G., Chang, M. C., Shaghasi, H., Ray, M. N., Averbukh, M., Hoang, S., Oorloff, M., Alcala, A., Vega, M., Mehta, H. H., Thorwald, M. A. & Crews, P. & 4 others, , Apr 3 2024, In: GeroScience. 46, p. 6009-6028Research output: Contribution to journal › Article › peer-review
Open Access -
In Vivo Evaluation of (-)-Zampanolide Demonstrates Potent and Persistent Antitumor Efficacy When Targeted to the Tumor Site
Takahashi-Ruiz, L., Morris, J. D., Crews, P., Johnson, T. & Risinger, A. L., 2022, In: Molecules. 27, 13, p. 4244Research output: Contribution to journal › Article › peer-review
Open Access -
Re-evaluation of the Fijianolide/Laulimalide Chemotype Suggests an Alternate Mechanism of Action for C-15/C-20 Analogs
Morris, J. D., Takahashi-Ruiz, L., Persi, L. N., Summers, J. C., McCauley, E. P., Chan, P. Y. W., Amberchan, G., Lizama-Chamu, I., Coppage, D. A., Crews, P., Risinger, A. L. & Johnson, T. A., 2022, In: ACS Omega. 7, 10, p. 8824-8832Research output: Contribution to journal › Article › peer-review
Open AccessFile
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Journal of Chemical Education (Journal)
Johnson, T. (Reviewer)
2022 → …Activity: Publication peer-review and editorial work › Publication peer-review
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Journal of Natural Products (Journal)
Johnson, T. (Reviewer)
2019 → …Activity: Publication peer-review and editorial work › Publication peer-review
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American Society of Pharmacognosy (External organization)
Johnson, T. A. (Member)
2007 → …Activity: Membership › Membership of network
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American Chemical Society (External organization)
Johnson, T. A. (Member)
2006 → …Activity: Membership › Membership of network
Press/Media
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Molecules derived from sea sponge show promising effects in cancer, mitochondrial function
6/5/24
1 item of Media coverage
Press/Media: Research
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Federal Contracts Awarded to Companies in California (April 12)
4/12/24
1 item of Media coverage
Press/Media: Research
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Here's where some Cincinnati-area athletes are going
11/19/23
1 item of Media coverage
Press/Media: Research