Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium falciparum

Roland A. Cooper; Michael T. Ferdig; Xin-zhuan Su; Lyann M. B. Ursos; Jiabing Mu; Takashi Nomura; David A. Fidock; Paul D. Roepe; Thomas E. Wellems

doi:<a href="http://molpharm.aspetjournals.org/content/61/1/35.short">10.1124/mol.61.1.35</a>

Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium falciparum

Roland A. Cooper, Michael T. Ferdig, Xin-zhuan Su, Lyann M. B. Ursos, Jiabing Mu, Takashi Nomura, David A. Fidock, Paul D. Roepe, Thomas E. Wellems

Research output: Contribution to journal › Article › peer-review

Original language	American English
Pages (from-to)	35-42
Number of pages	8
Journal	Molecular Pharmacology
Volume	61
Issue number	1
DOIs	https://doi.org/<a href="http://molpharm.aspetjournals.org/content/61/1/35.short">10.1124/mol.61.1.35</a>
State	Published - 2002
Externally published	Yes

Funding

Funders	Funder number
National Institute of Allergy and Infectious Diseases	Z01AI000483

ASJC Scopus Subject Areas

Molecular Medicine
Pharmacology

Disciplines

Parasitology

Access to Document

<a href="http://molpharm.aspetjournals.org/content/61/1/35.short">10.1124/mol.61.1.35</a>License: Unspecified

OpenUrl availability

Full text

Cite this

Cooper, R. A., Ferdig, M. T., Su, X., Ursos, L. M. B., Mu, J., Nomura, T., Fidock, D. A., Roepe, P. D., & Wellems, T. E. (2002). Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium falciparum. Molecular Pharmacology, 61(1), 35-42. https://doi.org/<a href="http://molpharm.aspetjournals.org/content/61/1/35.short">10.1124/mol.61.1.35</a>

Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium falciparum. / Cooper, Roland A.; Ferdig, Michael T.; Su, Xin-zhuan et al.
In: Molecular Pharmacology, Vol. 61, No. 1, 2002, p. 35-42.

Research output: Contribution to journal › Article › peer-review

Cooper, RA, Ferdig, MT, Su, X, Ursos, LMB, Mu, J, Nomura, T, Fidock, DA, Roepe, PD & Wellems, TE 2002, 'Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium falciparum', Molecular Pharmacology, vol. 61, no. 1, pp. 35-42. https://doi.org/<a href="http://molpharm.aspetjournals.org/content/61/1/35.short">10.1124/mol.61.1.35</a>

Cooper RA, Ferdig MT, Su X, Ursos LMB, Mu J, Nomura T et al. Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium falciparum. Molecular Pharmacology. 2002;61(1):35-42. doi: <a href="http://molpharm.aspetjournals.org/content/61/1/35.short">10.1124/mol.61.1.35</a>

@article{24c3c0f2c78a40afbd6477ed2f28f3a2,

title = "Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium falciparum",

author = "Cooper, \{Roland A.\} and Ferdig, \{Michael T.\} and Xin-zhuan Su and Ursos, \{Lyann M. B.\} and Jiabing Mu and Takashi Nomura and Fidock, \{David A.\} and Roepe, \{Paul D.\} and Wellems, \{Thomas E.\}",

year = "2002",

doi = "<a href={"}http://molpharm.aspetjournals.org/content/61/1/35.short{"}>10.1124/mol.61.1.35</a>",

language = "American English",

volume = "61",

pages = "35--42",

journal = "Molecular Pharmacology",

number = "1",

}

TY - JOUR

T1 - Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium falciparum

AU - Cooper, Roland A.

AU - Ferdig, Michael T.

AU - Su, Xin-zhuan

AU - Ursos, Lyann M. B.

AU - Mu, Jiabing

AU - Nomura, Takashi

AU - Fidock, David A.

AU - Roepe, Paul D.

AU - Wellems, Thomas E.

PY - 2002

Y1 - 2002

UR - http://molpharm.aspetjournals.org/content/61/1/35.full.pdf+html

U2 - <a href="http://molpharm.aspetjournals.org/content/61/1/35.short">10.1124/mol.61.1.35</a>

DO - <a href="http://molpharm.aspetjournals.org/content/61/1/35.short">10.1124/mol.61.1.35</a>

M3 - Article

VL - 61

SP - 35

EP - 42

JO - Molecular Pharmacology

JF - Molecular Pharmacology

IS - 1

ER -

Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium falciparum

Funding

ASJC Scopus Subject Areas

Disciplines

Access to Document

OpenUrl availability

Other files and links

Cite this