(+)-Altholactone Exhibits Broad Spectrum Immune Modulating Activity by Inhibiting the Activation of Pro-inflammatory Cytokines in RAW 264.7 Cell Lines

Tyler A. Johnson; Johann Sohn; Aidan E. Ward; Tanya L. Cohen; Nicholas D. Lorig-Roach; Haixia Chen; Ronaldo A. Pilli; Elizabeth A. Widjaja; Muhammad Hanafi; Leonardus B.S. Kardono; Puspa D. Lotulung; Kyria Boundy-Mills; Leonard F. Bjeldanes

doi:10.1016/j.bmc.2013.04.055

(+)-Altholactone Exhibits Broad Spectrum Immune Modulating Activity by Inhibiting the Activation of Pro-inflammatory Cytokines in RAW 264.7 Cell Lines

Tyler A. Johnson, Johann Sohn, Aidan E. Ward, Tanya L. Cohen, Nicholas D. Lorig-Roach, Haixia Chen, Ronaldo A. Pilli, Elizabeth A. Widjaja, Muhammad Hanafi, Leonardus B.S. Kardono, Puspa D. Lotulung, Kyria Boundy-Mills, Leonard F. Bjeldanes

Research output: Contribution to journal › Article › peer-review

Original language	American English
Pages (from-to)	4358-4364
Number of pages	7
Journal	Bioorganic & Medicinal Chemistry
Volume	21
Issue number	14
DOIs	https://doi.org/10.1016/j.bmc.2013.04.055
State	Published - Jul 15 2013
Externally published	Yes

Funding

The project described was supported by Grant Number U01TW008160 from the Fogarty International Center, the Office of Dietary Supplements, the National Science Foundation and the Department of Energy . This project was supported by the USDA Agricultural Food Research Initiative of the National Institute of Food and Agriculture, USDA , Grant #35621-04750 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the Fogarty International Center or the National Institutes of Health, the Office of Dietary Supplements, the National Science Foundation, the Department of Energy, or the Department of Agriculture. Additional funding was provided by NIH-MARC GM007910-31 (T.L.C.).

Funders	Funder number
National Science Foundation
National Institutes of Health
U.S. Department of Energy
Fogarty International Center	U01TW008160
Office of Dietary Supplements
U.S. Department of Agriculture
National Institute of Food and Agriculture	35621-04750

Keywords

Styryl lactones
(+)-Altholactone
(+)-Goniothalamin
Anti-inflammatory

Disciplines

Life Sciences
Medicine and Health Sciences

Access to Document

10.1016/j.bmc.2013.04.055License: Unspecified

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Cite this

Johnson, T. A., Sohn, J., Ward, A. E., Cohen, T. L., Lorig-Roach, N. D., Chen, H., Pilli, R. A., Widjaja, E. A., Hanafi, M., Kardono, L. B. S., Lotulung, P. D., Boundy-Mills, K., & Bjeldanes, L. F. (2013). (+)-Altholactone Exhibits Broad Spectrum Immune Modulating Activity by Inhibiting the Activation of Pro-inflammatory Cytokines in RAW 264.7 Cell Lines. Bioorganic & Medicinal Chemistry, 21(14), 4358-4364. https://doi.org/10.1016/j.bmc.2013.04.055

Johnson, TA, Sohn, J, Ward, AE, Cohen, TL, Lorig-Roach, ND, Chen, H, Pilli, RA, Widjaja, EA, Hanafi, M, Kardono, LBS, Lotulung, PD, Boundy-Mills, K & Bjeldanes, LF 2013, '(+)-Altholactone Exhibits Broad Spectrum Immune Modulating Activity by Inhibiting the Activation of Pro-inflammatory Cytokines in RAW 264.7 Cell Lines', Bioorganic & Medicinal Chemistry, vol. 21, no. 14, pp. 4358-4364. https://doi.org/10.1016/j.bmc.2013.04.055

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