Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism

Meredith E. Protas; Candace Hersey; Dawn Kochanek; Yi Zhou; Horst Wilkens; William R. Jeffery; Leonard I. Zon; Richard Borowsky; Clifford J. Tabin

doi:<a href="http://www.nature.com/ng/journal/v38/n1/full/ng1700.html">10.1038/ng1700</a>

Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism

Meredith E. Protas
, Candace Hersey
, Dawn Kochanek
, Yi Zhou
, Horst Wilkens
, William R. Jeffery
, Leonard I. Zon
, Richard Borowsky
, Clifford J. Tabin

Department of Genetics, Harvard Medical School
Children’s Hospital Stem Cell Program, Department of Hematology/Oncology, Howard Hughes Medical Institute, Children’s Hospital Boston
Cave Biology Research Group, Department of Biology, New York University
Zoological Institute and Zoological Museum, University of Hamburg
Department of Biology, University of Maryland

Research output: Contribution to journal › Article › peer-review

Original language	American English
Pages (from-to)	107-111
Number of pages	5
Journal	Nature Genetics
Volume	38
Issue number	1
DOIs	https://doi.org/<a href="http://www.nature.com/ng/journal/v38/n1/full/ng1700.html">10.1038/ng1700</a>
State	Published - Jan 2006
Externally published	Yes

Funding

This work was supported by US National Science Foundation grant IBN0217178 to R. Borowsky and C.J. Tabin. The authors thank L. Mekios for phenotyping and fish maintenance, the Bennett group for the use of the melan-p cell line, T. Matsuda for the pUB-GFP construct, R.C. Albertson for critical reading of the manuscript, and C. Peichel, R.V. Pearse II, J.L. Galloway and J. Rivera-Feliciano for help and advice.

Funders	Funder number
National Science Foundation	IBN0217178
National Eye Institute	R01EY014619

ASJC Scopus Subject Areas

Genetics

Keywords

Amblyopsidae
Albinos and albinism
Genomes
Vertebrates
Proteins
Microbiological assay

Disciplines

Ecology and Evolutionary Biology

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<a href="http://www.nature.com/ng/journal/v38/n1/full/ng1700.html">10.1038/ng1700</a>License: Unspecified

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title = "Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism",

keywords = "Amblyopsidae, Albinos and albinism, Genomes, Vertebrates, Proteins, Microbiological assay",

author = "Protas, \{Meredith E.\} and Candace Hersey and Dawn Kochanek and Yi Zhou and Horst Wilkens and Jeffery, \{William R.\} and Zon, \{Leonard I.\} and Richard Borowsky and Tabin, \{Clifford J.\}",

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AU - Protas, Meredith E.

AU - Hersey, Candace

AU - Kochanek, Dawn

AU - Zhou, Yi

AU - Wilkens, Horst

AU - Jeffery, William R.

AU - Zon, Leonard I.

AU - Borowsky, Richard

AU - Tabin, Clifford J.

PY - 2006/1

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KW - Amblyopsidae

KW - Albinos and albinism

KW - Genomes

KW - Vertebrates

KW - Proteins

KW - Microbiological assay

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U2 - <a href="http://www.nature.com/ng/journal/v38/n1/full/ng1700.html">10.1038/ng1700</a>

DO - <a href="http://www.nature.com/ng/journal/v38/n1/full/ng1700.html">10.1038/ng1700</a>

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SP - 107

EP - 111

JO - Nature Genetics

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IS - 1

ER -

Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism

Funding

ASJC Scopus Subject Areas

Keywords

Disciplines

Access to Document

OpenUrl availability

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