Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila

  • Alan Pearson
  • , Katalin Baksa
  • , Mika Rämet
  • , Meredith E. Protas
  • , Mary McKee
  • , Dennis Brown
  • , R. Alan B. Ezekowitz

Research output: Contribution to journalArticlepeer-review

Original languageAmerican English
Pages (from-to)815-824
Number of pages10
JournalMicrobes and Infection
Volume5
Issue number10
StatePublished - Aug 2003
Externally publishedYes

Funding

We thank E. Gateff, I. Kiss, J.-M. Reicchart and J. Hoffmann for providing Drosophila strains, and J. Zallen and E. Schejter for generously providing the D-SCAR antibody. We thank T. Stossel and J. Hartwig and many members of the Lab of Developmental Immunology at MGH, particularly A. Harikrishnan, C. Kocks, and C. Dearolf, for their support and advice, and C. Kocks for her critical reading of this manuscript. This work was supported by National Institutes of Health grants 5PO1 AI44220 (R.A.B.E.), HD 40793 (S.B.) and DK 38452 (S.B and D.B.). A.P. was supported by an American Cancer Society Postdoctoral Fellowship (PF-99-324-01) and M.R. by the Academy of Finland. The microscopy core facility used in this work was partially supported by a Center grant for the Study of Inflammatory Bowel Disease DK 43351 and a Boston Area Diabetes Endocrinology Research Center grant DK 57521.

FundersFunder number
National Institutes of HealthDK 38452, HD 40793
American Cancer SocietyPF-99-324-01
National Institute of Allergy and Infectious DiseasesP01AI044220
Boston Area Diabetes Endocrinology Research CenterDK 57521
Academy of Finland

    ASJC Scopus Subject Areas

    • Microbiology
    • Immunology
    • Infectious Diseases

    Keywords

    • Cytoskeleton
    • Drosophila
    • Innate immunity
    • Phagocytosis

    Disciplines

    • Evolution
    • Immunology and Infectious Disease

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