Identification of the First Marine-Derived Opioid Receptor "Balanced" Agonist with a Signaling Profile That Resembles the Endorphins.

Tyler A. Johnson, Laura Millan-Lobo, Tao Che, Madeline Ferwerda, Eptisam Lambu, Nicole L. McIntosh, Fei Li, Li He, Nicholas Lorig-Roach, Phillip Crews, Jennifer L. Whistler

Research output: Contribution to journalArticlepeer-review

Original languageAmerican English
JournalDefault journal
Volume8
DOIs
StatePublished - Mar 15 2017

Keywords

  • Analgesics
  • Opioid
  • Animals
  • Computer Simulation
  • Cyclic AMP
  • Endocytosis
  • Endorphins
  • GTP-Binding Proteins
  • HEK293 Cells
  • Humans
  • Indoles
  • Locomotion
  • Male
  • Mice
  • Transgenic
  • Models
  • Molecular
  • Naphthyridines
  • Porifera
  • Receptors
  • delta
  • Signal Transduction
  • Spectrometry
  • Mass
  • Electrospray Ionization
  • Swimming
  • beta-Arrestins

Disciplines

  • Biochemistry
  • Natural Products Chemistry and Pharmacognosy

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