Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries.

Tyler A. Johnson, Johann Sohn, Yvette M. Vaske, Kimberly N. White, Tanya L. Cohen, Helene C. Vervoort, Karen Tenney, Frederick A. Valeriote, Leonard F. Bjeldanes, Phillip Crews

Research output: Contribution to journalArticlepeer-review

Original languageAmerican English
JournalDefault journal
Volume20
DOIs
StatePublished - Jul 15 2012
Externally publishedYes

Keywords

  • Alkaloids
  • Animals
  • Azepines
  • Chemokine CCL2
  • Chromatography
  • High Pressure Liquid
  • HCT116 Cells
  • Humans
  • I-kappa B Kinase
  • Immunologic Factors
  • Interleukin-6
  • Lipopolysaccharides
  • Macrophages
  • Mass Spectrometry
  • Mice
  • Myxococcales
  • NF-kappa B
  • Nitric Oxide Synthase Type II
  • Phosphorylation
  • Porifera
  • Tumor Necrosis Factor-alpha

Disciplines

  • Biochemistry
  • Natural Products Chemistry and Pharmacognosy

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