Novel Flexible Heteroarotinoid, SL-1-18, Promotes ERα Degradation to Inhibit Breast Cancer Cell Growth

  • Maryam M. Fallatah
  • , Shengquan Liu
  • , Mary B. Sevigny
  • , Hongye Zou
  • , Maggie C. Louie

Research output: Contribution to journalArticlepeer-review

Original languageAmerican English
Pages (from-to)82-91
Number of pages10
JournalCancer Letters
Volume408
DOIs
StatePublished - 2017

Funding

This work was supported by grant funding from Dominican University, School of Health and Natural Sciences Research grant to M.C.L. and Touro University-CA, College of Pharmacy Intramural Research Award Program (IRAP) to S.L.

Funders
Touro University, California

    ASJC Scopus Subject Areas

    • Oncology
    • Cancer Research

    Keywords

    • Antineoplastic Agents
    • Apoptosis
    • Breast Neoplasms
    • Cell Cycle
    • Cell Proliferation
    • Chromans
    • Chrysenes
    • Estrogen Receptor alpha
    • Female
    • Gene Expression Regulation
    • Neoplastic
    • Humans
    • Proteasome Endopeptidase Complex
    • Proteolysis
    • Thiones
    • Thiourea
    • Tumor Cells
    • Cultured
    • Ubiquitination
    • Estrogen receptor
    • Flexible heteroarotinoid
    • SHetA2
    • Novel therapeutics
    • Breast cancer
    • Selective ER down-regulators

    Disciplines

    • Genetic Phenomena
    • Neoplasms

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