ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer

Jujian Wang; June X. Zou; Xiaoqian Xue; Demin Cai; Yan Zhang; Zguhuab Duan; Qiuping Xiang; Joy C. Yang; Maggie C Louie; Alexander D Borowsky; Allen C Gao; Christopher P. Evans; Kit S. Lam; Jianzhen Xu; Hsing-Jien Kung; Ronald M. Evans; Yong Xu; Hong-Wu Chen

doi:<a href="http://www.nature.com/nm/journal/v22/n5/full/nm.4070.html">10.1038/nm.4070</a>

ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer

Jujian Wang, June X. Zou, Xiaoqian Xue, Demin Cai, Yan Zhang, Zguhuab Duan, Qiuping Xiang, Joy C. Yang, Maggie C Louie, Alexander D Borowsky, Allen C Gao, Christopher P. Evans, Kit S. Lam, Jianzhen Xu, Hsing-Jien Kung, Ronald M. Evans, Yong Xu, Hong-Wu Chen

Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis
Institute of Chemical Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
Department of Urology, School of Medicine, University of California, Davis
Department of Pathology and Laboratory Medicine, School of Medicine, University of California, Davis
Shantou University Medical College

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Nature Medicine
Volume	22
DOIs	https://doi.org/<a href="http://www.nature.com/nm/journal/v22/n5/full/nm.4070.html">10.1038/nm.4070</a>
State	Published - May 2016

Keywords

Cancer
castration-resistant prostate cancer

Disciplines

Cancer Biology
Medicine and Health Sciences

Access to Document

<a href="http://www.nature.com/nm/journal/v22/n5/full/nm.4070.html">10.1038/nm.4070</a>License: Unspecified

OpenUrl availability

Full text

Cite this

Wang, J., Zou, J. X., Xue, X., Cai, D., Zhang, Y., Duan, Z., Xiang, Q., Yang, J. C., Louie, M. C., Borowsky, A. D., Gao, A. C., Evans, C. P., Lam, K. S., Xu, J., Kung, H.-J., Evans, R. M., Xu, Y., & Chen, H.-W. (2016). ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nature Medicine, 22. https://doi.org/<a href="http://www.nature.com/nm/journal/v22/n5/full/nm.4070.html">10.1038/nm.4070</a>

Wang, J, Zou, JX, Xue, X, Cai, D, Zhang, Y, Duan, Z, Xiang, Q, Yang, JC, Louie, MC, Borowsky, AD, Gao, AC, Evans, CP, Lam, KS, Xu, J, Kung, H-J, Evans, RM, Xu, Y & Chen, H-W 2016, 'ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer', Nature Medicine, vol. 22. https://doi.org/<a href="http://www.nature.com/nm/journal/v22/n5/full/nm.4070.html">10.1038/nm.4070</a>

@article{2ca9f24e961747c7832bf2146bbf8c21,

title = "ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer",

keywords = "Cancer, castration-resistant prostate cancer",

author = "Jujian Wang and Zou, {June X.} and Xiaoqian Xue and Demin Cai and Yan Zhang and Zguhuab Duan and Qiuping Xiang and Yang, {Joy C.} and Louie, {Maggie C} and Borowsky, {Alexander D} and Gao, {Allen C} and Evans, {Christopher P.} and Lam, {Kit S.} and Jianzhen Xu and Hsing-Jien Kung and Evans, {Ronald M.} and Yong Xu and Hong-Wu Chen",

year = "2016",

month = may,

doi = "<a href={"}http://www.nature.com/nm/journal/v22/n5/full/nm.4070.html{"}>10.1038/nm.4070</a>",

language = "American English",

volume = "22",

journal = "Nature Medicine",

}

TY - JOUR

T1 - ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer

AU - Wang, Jujian

AU - Zou, June X.

AU - Xue, Xiaoqian

AU - Cai, Demin

AU - Zhang, Yan

AU - Duan, Zguhuab

AU - Xiang, Qiuping

AU - Yang, Joy C.

AU - Louie, Maggie C

AU - Borowsky, Alexander D

AU - Gao, Allen C

AU - Evans, Christopher P.

AU - Lam, Kit S.

AU - Xu, Jianzhen

AU - Kung, Hsing-Jien

AU - Evans, Ronald M.

AU - Xu, Yong

AU - Chen, Hong-Wu

PY - 2016/5

Y1 - 2016/5

KW - Cancer

KW - castration-resistant prostate cancer

U2 - <a href="http://www.nature.com/nm/journal/v22/n5/full/nm.4070.html">10.1038/nm.4070</a>

DO - <a href="http://www.nature.com/nm/journal/v22/n5/full/nm.4070.html">10.1038/nm.4070</a>

M3 - Article

VL - 22

JO - Nature Medicine

JF - Nature Medicine

ER -