@article{1baac7541b214a8bbf6489983f379063,
title = "The aignopsanes, a new class of sesquiterpenes from selected chemotypes of the sponge Cacospongia mycofijiensis",
abstract = "A survey of individual specimens of northern Papua New Guinea derived Cacospongia mycofijiensis has yielded novel sesquiterpenes, aignopsanoic acid A (1), methyl aignopsanoate A (2), and isoaignopsanoic acid A (3). The structures and absolute configurations of 1-3 were established using NMR data, X-ray crystallography results, and an analysis of CD properties. Two of these metabolites, 1 and 2, were moderately active against Trypanosoma brucei, the parasite responsible for sleeping sickness.",
keywords = "Animals, Crystallography, X-Ray, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Papua New Guinea, Parasitic Sensitivity Tests, Porifera, Sesquiterpenes, Trypanosoma brucei brucei, Trypanosomiasis, African",
author = "Johnson, \{Tyler A.\} and Taro Amagata and Sashidhara, \{Koneni V.\} and Oliver, \{Allen G.\} and Karen Tenney and Teatulohi Matainaho and Ang, \{Kenny Kean-Hooi\} and McKerrow, \{James H\} and Phillip Crews",
year = "2009",
month = mar,
day = "30",
doi = "10.1021/ol900446d",
language = "American English",
volume = "11",
pages = "1975--1978",
journal = "Organic Letters",
number = "9",
}