The marine sponge metabolite mycothiazole: a novel prototype mitochondrial complex I inhibitor.

J Brian Morgan, Fakhri Mahdi, Yang Liu, Veena Coothankandaswamy, Mika B. Jekabsons, Tyler A. Johnson, Koneni V. Sashidhara, Phillip Crews, Dale G. Nagle, Yu-Dong Zhou

Research output: Contribution to journalArticlepeer-review

Original languageAmerican English
JournalDefault journal
Volume18
DOIs
StatePublished - Aug 15 2010
Externally publishedYes

Keywords

  • Animals
  • Cell Line
  • Tumor
  • Cell Survival
  • Cells
  • Cultured
  • Electron Transport Complex I
  • Enzyme Inhibitors
  • Female
  • Gene Expression Regulation
  • Humans
  • Hypoxia-Inducible Factor 1
  • alpha Subunit
  • Neovascularization
  • Pathologic
  • Neurons
  • Porifera
  • Rats
  • Thiazoles

Disciplines

  • Biochemistry
  • Natural Products Chemistry and Pharmacognosy

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